Endocrine Abstracts

Non-alcoholic steatohepatitis (NASH) is a clinical entity characterized by the infiltration of fat into the liver associated with hepatic inflammation. The etiology is unknown, however its most frequently observed in patients with type 2 diabetes mellitus (DM 2), obesity or insulin resistance. DM 2 is an independent risk factor for the progression of NASH. Usually there are no symptoms, so it is not possible to estimate its prevalence. The treatment focuses on the control of a...

Non-alcoholic steatohepatitis (NASH) is a clinical entity characterized by the infiltration of fat into the liver associated with hepatic inflammation. The etiology is unknown, however its most frequently observed in patients with type 2 diabetes mellitus (DM 2), obesity or insulin resistance. DM 2 is an independent risk factor for the progression of NASH. Usually there are no symptoms, so it is not possible to estimate its prevalence. The treatment focuses on the control of a...

Introduction: Cushing’s disease (CD) is a potentially fatal disease caused by corticotrophic adenoma of the pituitary gland. Crooke Cell Adenomas (CCA) are a rare variant characterized by cytoplasmic ring deposits of cytokeratin filaments. They are usually aggressive macroadenomas with a higher rate of recurrence and malignancy.Clinical case: A 36 year old man, with 34 kg weight gain and uncontrolled hypertension for 4 years presented at the Emerge...

Introduction: Pancreas transplantation is an established treatment for selected patients with type 1 diabetes mellitus (T1DM) and severe chronic kidney disease (CKD), reducing mortality and morbidity.Methods: We retrospectively reviewed the cases of pancreas transplantation performed at our centre from 1-January-2011 to 30-June-2016.Results: In this period, 53 transplants were performed: 48 simultaneous pancreas-kidney transplants ...

IntroductionHypocalcaemia is a complication of total thyroidectomy (TT) and may be more frequent in patients with Graves’ disease. The reason for this increased risk is unclear and its occurrence has been associated with: ophthalmopathy severity, preoperative calcaemia and reimplantation of parathyroid glands.ObjectivesTo evaluate the risk factors for transient hypocalcaemia (TH) and definitive hypoparat...

Introduction: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism (PHPT). In recent years minimally invasive surgical techniques have challenged the traditional bilateral neck exploration. There are different imaging techniques for preoperative location of parathyroid adenomas. In this study the authors review the role of Doppler ultrasound focusing on its safety, availability and affordability.Aim: To evaluate the role of Doppl...

IntroductionDiabetic foot is one of the most devastating of chronic complications of diabetes mellitus (DM) and is responsible for about 25% of hospitalizations. Worldwide, the diabetic foot represents the main cause of non-traumatic lower limb amputation.Aim of the studyIdentification of risk factors for foot amputation among in patients hospitalized for diabetic foot in a tertiary public hospital in Portuga...